ABKYU

In vivo VHH Discovery for Cell Surface and multispanning targets

Utilizing Advanced In Vivo Strategies
for Rapid VHH Discovery

Genetic Immunization Strategies

Immune Profiling of Study Animals

Proprietary DNA Protocols

Rapid Immune Potentiation (60-90 days)

Next-Gen Immune Libraries

Custom library construction

Protein and cell-based panning

Round-Round Deep NGS

Fully owned partner deliverables

VHH Humanization and Optimization

Rapid in-silico humanization

Affinity maturation

Structured based optimization

ABKYU Difference

Speed

Next generation sequencing and bioinformatics pipelines capture high value VHHs

Rapid VHH make-test cycles and diverse repertoire characterization strategies allow for early capture of hits with ideal biophysical and functional properties

Ideal Biophysical Profiles

Identification of naturally derived VHHs with:

A range of high affinities

High specificity to soluble and cell surface targets

Ideal developability characteristics

Accessible Business Terms


No royalties or milestones

Fully owned partner deliverables

Success gated service fees

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